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Western blot analysis of lysed extracts from MDA cells using ICAM-1 (Ab-512).
Western blot analysis of lysed extracts from MDA cells using ICAM-1 (Ab-512).

ICAM 1 (Ab 512) Antibody

CATALOG NUMBER: 79-545

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
ICAM-1 (Ab-512) antibody was raised against a peptide sequence around aa. 510~514 (K-K-Y-R-L) derived from Human ICAM-1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of total ICAM-1 protein.
Predicted Molecular Weight:
92 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
ICAM1
Additional Names:
BB2, CD54, P3.58, ICA1, ICAM1
Protein Accession Number:
NP_000192.2
Protein Gi Number:
167466198
Ncbi Gene Id Number:
3383
Background:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Background Reference 1:
Greenwood J, et al. (2003) J Immunol; 171 (4): 2099-2108. Zhou Z, et al. (2005) Eur J Pharmacol; 513 (1-2): 1-8. Chen YH, et al. (2001) J Cell Biochem; 82 (3): 512-521

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-545

List Size:
0.1 mg

List Price:

$370.00

Datasheet
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