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IFI16 (CT) Peptide

CATALOG NUMBER: 9641P

Tested Applications:
Blocking
Specifications
Peptide Aa Location:
16 amino acids near the carboxyl terminus of human IFI16.
Species:
Human
Tested Applications:
Blocking
Application Note:
IFI16 (CT) Peptide is used for blocking the activity of IFI16 (CT) Antibody.
Physical State:
Liquid
Buffer:
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and ≤0.09% sodium azide
Concentration:
200 ug/mL
Storage Conditions:
Store ULBP1 peptide at -20°C, stable for one year.
Ncbi Official Symbol:
IFI16
Additional Names:
IFI16 Antibody: Gamma-interferon-inducible protein 16, Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator, IFNGIP1
Protein Accession Number:
Q16666.3
Protein Gi Number:
118572657
Ncbi Gene Id Number:
3428
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
IFI16 Antibody: IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer. Increased expression of IFI16 predicts adverse prognosis in multiple myeloma. IFI16 isoforms with cytoplasmic and nuclear locations play differential roles in recognizing invaded DNA viruses. IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection. Nuclear sensor IFI16 inhibits the function of Hepatitis B virus covalently closed circular DNA by integrating innate immune activation and epigenetic suppression.
Background Reference 1:
Ka et al. Cell Rep. 2021; 37(12):110138
Background Reference 2:
Huang et al. Pharmacogenomics J. 2021; 21(4):520-532
Background Reference 3:
Li et al. J Immunol. 2021; 207(11):2699-2709
Background Reference 4:
Jiang et al. Nat Microbiol. 2021; 6(7):932-945
Background Reference 5:
Yang et al. Hepatology 2020; 71(4):1154-1169

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

9641P

List Size:
0.05 mg

List Price:

$119.00

Datasheet
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