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IFN gamma Recombinant Protein

CATALOG NUMBER: 40-472

Specifications
source-species:
E. coli
Species:
Rat
source-species:
E. coli
Recombinant Protein Sequence:
MQGTLIESLE SLKNYFNSSS MDAMEGKSLL LDIWRNWQKD GNTKILESQI ISFYLRLFEV LKDNQAISNN ISVIESHLIT NFFSNSKAKK DAFMSIAKFE VNNPQIQHKA VNELIRVIHQ LSPESSLRKR KRSRC
Biological Activity:
The ED50 was determined by a cytopathic affect inhibition assay with murine L929 cells challenged with EMC virus was < 0.1 ng/mL, corresponding to a specific activity of > 1 x 107 units/mg.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized IFN gamma recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IFN gamma is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IFN gamma recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
Ifng
Additional Names:
IFNG2, Interferon gamma, IFN-gamma
Protein Accession Number:
NP_620235.1
Protein Gi Number:
20302055
Ncbi Gene Id Number:
25712
Background:
IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma is species-specific and is biologically active only in human and primate cells. Recombinant rat IFN-gamma is a 15.6 kDa protein containing 135 amino acid residues.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-472

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $215.00 through $323.00

Datasheet
Shipping Info

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