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IFN lamda 1 Recombinant Protein

CATALOG NUMBER: 40-280

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
PTSKPTTTGK GCHIGRFKSL SPQELASFKK ARDALEESLK LKNWSCSSPV FPGNWDLRLL QVRERPVALE AELALTLKVL EAAAGPALED VLDQPLHTLH HILSQLQACI QPQPTAGPRP RGRLHHWLHR LQEAPKKESA GCLEASVTFN LFRLLTRDLK YVADGNLCLR TSTHPEST
Biological Activity:
Recombinant human IFN - lambda 1 induces phosphorylation of STAT2.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized IFN lamda 1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IFN lamda 1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IFN lamda 1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
IFNL1
Additional Names:
IL29, IL-29, IL29, ZCYTO21, Interferon lambda-1, Cytokine Zcyto21, IFN-lambda-1
Protein Accession Number:
NP_742152.1
Protein Gi Number:
26024325
Ncbi Gene Id Number:
282618
Background:
IFN λ-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas use a distinct receptor system composed of an IFN-λR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces anti-viral defense similar but distinct than the type I Interferons. (Kotenko, SV. et al. Nat Immunology 2003 [1] p. 69-77). Recombinant human IFN-λ 1 is a 19.8 kDa protein containing 178 amino acid residues.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-280

List Size:
0.005 mg, 0.02 mg

List Price:

Price range: $215.00 through $323.00

Datasheet
Shipping Info

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