IFN lamda 2 Recombinant Protein

CATALOG NUMBER: 40-279

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
PVARLHGALP DARGCHIAQF KSLSPQELQA FKRAKDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV
Biological Activity:
Biological activity was determined by its ability to activate STAT following receptor - ligand interaction.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized IFN lamda 2 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IFN lamda 2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IFN lamda 2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
IFNL2
Additional Names:
IL28A, IL-28A, IL28A, ZCYTO20, Interferon lambda-2, Cytokine Zcyto20, IFN-lambda-2
Protein Accession Number:
NP_742150.1
Protein Gi Number:
26024321
Ncbi Gene Id Number:
282616
Background:
IFN-λ-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-λR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces anti-viral defense similar but distinct than the type I Interferons.(Kotenko, SV. et al. Nat Immunology 2003 [1] p. 69-77). Recombinant human IFN-λ 2 is a 19.6 kDa protein containing 174 amino acid residues.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-279

List Size:
0.005 mg, 0.02 mg

List Price:

Price range: $215.00 through $323.00

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