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Western blot analysis of IFLTD1 in rat liver tissue lysate with IFLTD1 antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of IFTLD1 in rat liver tissue with IFTLD1 antibody at 5 μg/mL.
Western blot analysis of IFLTD1 in rat liver tissue lysate with IFLTD1 antibody at (A) 1 and (B) 2 μg/mL.
Trial Size

IFTLD1 Antibody

CATALOG NUMBER: 6447

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
IFLTD1 antibody was raised against an 19 amino acid synthetic peptide near the center of human IFLTD1.
The immunogen is located within amino acids 200 - 250 of IFTLD1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC-P, WB
Application Note:
IFLTD1 antibody can be used for detection of IFLTD1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.
Specificity:
At least four isoforms of IFLTD1 are known to exist; this antibody will detect all but isoform 4
Positive Control 1:
Cat. No. 1462 - Rat Lung Tissue Lysate
Purification:
IFTLD1 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
IFTLD1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
IFTLD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
IFLTD1
Additional Names:
IFTLD1 Antibody: PAS1C1, Intermediate filament tail domain-containing protein 1
Protein Accession Number:
NP_001139200
Protein Gi Number:
224593273
Ncbi Gene Id Number:
160492
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
IFTLD1 Antibody: The intermediate filament tail domain-containing protein (IFLTD1) was initially identified as a candidate gene for pulmonary adenoma susceptibility 1 gene in mice. Transcripts of the gene were only detected in mouse lung tissue from strains carrying the Pas1-susceptible allele. Expression of different alleles of this gene in lung cancer cell lines resulted in different levels of colony formation in in vitro colony formation assays, suggesting that allelic variants of this gene can modulate growth of human cancer cells.
Background Reference 1:
Wang M, Lemon WJ, Liu G, et al. Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines. Cancer Res. 2003; 63:3317-24.
Background Reference 2:
Wang M, Futamura M, Wang Y, et al. Pasc1 is a candidate for the mouse pulmonary adenoma susceptibility 1 locus. Oncogene 2005; 24:1958-63.
Background Reference 3:
Galbiati F, Pettinicchio A, Dragani TA, et al. Allelic effects of mouse Pas candidate genes in human lung cancer cell lines. Cancer Lett. 244:176-81.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

6447

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
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