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IGF-1 Antibody [IGF1/1020]

CATALOG NUMBER: 33-409

Clonality:
Monoclonal
Tested Applications:
Flow, IF, Neutralization Assay
Host Species:
Mouse
Species Reactivity:
Human, Mouse, Rabbit, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human, Mouse, Rabbit, Rat
Immunogen:
Full-length recombinant human IGF1 protein was used as the immunogen for the IGF-1 antibody.
Conjugate:
Unconjugated
Tested Applications:
Flow, IF, Neutralization Assay
Application Note:
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
Immunofluorescence: 1-2 ug/ml
Functional Activity: In-vitro neutralization of biological activity of IGF-1 (Order SAF formulation)
Optimal dilution of the IGF-1 antibody should be determined by the researcher.
Purification:
Protein G affinity chromatography
Clonality:
Monoclonal
Isotype:
IgG1, kappa
Physical State:
Liquid
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Storage Conditions:
Aliquot and Store at 2-8°C. Avoid freez-thaw cycles.
Ncbi Official Symbol:
IGF1
Additional Names:
IGF1, OTTHUMP00000195084, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor 1, IGFI, IGF1A, IBP1
Ncbi Gene Id Number:
3479
User Note:
Optimal dilutions for each application to be determined by the researcher
Background:
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

33-409

List Size:
100 ug

List Price:

$626.00

Datasheet
Shipping Info

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