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Western blot analysis of lysed extracts from 293 cells using IGF-1R (Ab-1161).
<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IGF-1R (Ab-1161).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed MCF cells using IGF-1R (Ab-1161).
Western blot analysis of lysed extracts from 293 cells using IGF-1R (Ab-1161).

IGF 1R (Ab 1161) Antibody

CATALOG NUMBER: 79-316

Clonality:
Polyclonal
Tested Applications:
IF, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
IGF-1R (Ab-1161) antibody was raised against a peptide sequence around aa.1159~1163 (D-I-Y-E-T) derived from Human IGF-1R .
Conjugate:
Unconjugated
Tested Applications:
IF, IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Specificity:
This antibody detects endogenous level of total IGF-1R protein.
Predicted Molecular Weight:
200 95 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
IGF1R
Additional Names:
IGFR, CD221, IGFIR, JTK13, MACS, PRKCSL, Insulin-like growth factor I receptor, IGF1R, kinase IGF1R
Protein Accession Number:
NP_000866.1
Protein Gi Number:
4557665
Ncbi Gene Id Number:
3480
Background:
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
Background Reference 1:
Li S, et al. (1994) J Biol Chem; 269 (51) . Hernandez-Sanchez C, et al. (1995) J Biol Chem.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-316

List Size:
0.1 mg

List Price:

$370.00

Datasheet
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