IGF1 Antibody [M23]

CATALOG NUMBER: 33-144

Clonality:
Monoclonal
Tested Applications:
Flow, IF, inhibition assay
Host Species:
Mouse
Species Reactivity:
Human, Mouse, Rabbit, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human, Mouse, Rabbit, Rat
Immunogen:
Purified human IGF1 protein was used as the immunogen for this antibody.
Conjugate:
Unconjugated
Tested Applications:
Flow, IF, inhibition assay
Application Note:
Flow Cytometry: 0.5-1 ug/million cells
IF: 1-2 ug/ml
Functional Activity: In vitro inhibition of IGF1 Activity; order BSA/azide free format
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
Purification:
Protein G affinity chromatography
Clonality:
Monoclonal
Isotype:
IgG1, kappa
Physical State:
Liquid
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Storage Conditions:
Aliquot and Store at 2-8°C. Avoid freez-thaw cycles.
Ncbi Official Symbol:
IGF1
Additional Names:
IGF1, OTTHUMP00000195084, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor 1, IGFI, IGF1A, IBP1
Ncbi Gene Id Number:
3479
User Note:
Optimal dilutions for each application to be determined by the researcher
Background:
This antibody is specific to IGF1 (Insulin like Growth Factor 1) and shows minimal cross-reaction with IGF11, Proinsulin, MSF, and Insulin. IGF1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF1B while isoform 2 is known as IGF1A. IGF1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of the IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

33-144

List Size:
100 ug

List Price:

$626.00

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