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Western blot analysis of extracts from COS-7 cells treated with UV using IGF2R (Phospho-Ser2409) Antibody. The lane on the right is treated with the antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human brain tissue using IGF2R (Phospho-Ser2409) antibody (left) or the same antibody preincubated with blocking peptide (right).
Western blot analysis of extracts from COS-7 cells treated with UV using IGF2R (Phospho-Ser2409) Antibody. The lane on the right is treated with the antigen-specific peptide.

IGF2R (phospho Ser2409) Antibody

CATALOG NUMBER: 79-826

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
IGF2R (phospho Ser2409) antibody was raised against a peptide sequence around phosphorylation site of Serine 2409 (Q-D-S (p)-E-D) derived from Human IGF2R.
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
The antibody detects endogenous levels of IGF2R only when phosphorylated at serine 2409.
Predicted Molecular Weight:
300 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
IGF2R
Additional Names:
CI-MPR, CI-MPR, MPR300, MPRI
Protein Accession Number:
NP_000867.2
Protein Gi Number:
317373416
Ncbi Gene Id Number:
3482
Background:
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Background Reference 1:
Morgan D.O., Nature 329:301-307(1987).
Background Reference 2:
Oshima A., J. Biol. Chem. 263:2553-2562(1988).
Background Reference 3:
Killian J.K., Mamm. Genome 10:74-77(1999)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-826

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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