IGFBP 3 Antibody

CATALOG NUMBER: 79-770

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
IGFBP-3 antibody  was raised against a peptide sequence around aa.185~189 (R-Y-K-V-D) derived from Human IGFBP-3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of total IGFBP-3 protein.
Predicted Molecular Weight:
24 - 41 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
IGFBP3
Additional Names:
IBP3, BP-53, IBP3
Protein Accession Number:
NP_001013416.1
Protein Gi Number:
62243248
Ncbi Gene Id Number:
3486
Background:
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Background Reference 1:
Roghani M., Segovia B., Whitechurch O., Binoux M. Growth Regul. 1:125-130 (1991) Ikonen M., Liu B., Hashimoto Y., Ma L., Lee K. W., Niikura T., Nishimoto I., Cohen P. Proc. Natl. Acad. Sci. U. S. A. 100:13042-13047 (2003) Zhou W., Ross M. M., Tessitore A., Ornstein D., Vanmeter A., Liotta L. A., Petricoin E. F. IIIJ. Proteome Res. 8:5523-5531 (2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-770

List Size:
0.1 mg

List Price:

$370.00

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