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Western blot analysis of extracts from Rat brain tissue using IGFBP-3 (Phospho-Ser183) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from Rat brain tissue using IGFBP-3 (Phospho-Ser183) Antibody. The lane on the right is treated with the antigen-specific peptide.

IGFBP-3 (phospho Ser183) Antibody

CATALOG NUMBER: 80-047

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
IGFBP-3 (phospho Ser183) antibody was raised against a peptide sequence around phosphorylation site of serine 183 (K-D-S (p)-Q-R) derived from Human IGFBP-3 .
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous level of IGFBP-3 only when phosphorylated at serine 183.
Predicted Molecular Weight:
30 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
IGFBP3
Additional Names:
IBP-3, IBP3, IGF-binding protein 3, IGFBP3, Insulin-like growth factor binding protein 3 precursor
Protein Accession Number:
NP_000589.2
Protein Gi Number:
62243248
Ncbi Gene Id Number:
3486
Background:
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Background Reference 1:
Zhang Q, Steinle JJ (2013)Invest Ophthalmol Vis Sci 54, 3052-7 . Cobb LJ, Liu B, Lee KW, Cohen P (2006) Cancer Res 66, 10878-84 .

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

80-047

List Size:
0.1 mg

List Price:

$355.00

Out of stock

Datasheet
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