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Western blot analysis of extracts from HepG2 cells treated with TNF using IKK- alpha/ beta (Phospho-Ser180/181) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from HepG2 cells treated with TNF using IKK- alpha/ beta (Phospho-Ser180/181) Antibody. The lane on the right is treated with the antigen-specific peptide.

IKK- alpha/ beta (phospho Ser180/181) Antibody

CATALOG NUMBER: 79-981

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
IKK- alpha/ beta (phospho Ser180/181) antibody was raised against a peptide sequence around phosphorylation site of serine 180/181 (C-T-S (p)-F-V) derived from Human IKK- alpha/ beta.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous level of IKK- alpha/beta only when phosphorylated at serine 180/181.
Predicted Molecular Weight:
85 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
CHUK
Additional Names:
FLJ40509, I-kappa-B kinase, IKBKB, kinase beta, NFKBIKB
Protein Accession Number:
NP_001269.3
Protein Gi Number:
62241001
Ncbi Gene Id Number:
1147
Background:
Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.
Background Reference 1:
Hafeez BB, et al. (2008) Cancer Res 68, 8564-72
Background Reference 2:
Cahill CM, Rogers JT (2008) J Biol Chem 283, 25900-12
Background Reference 3:
Encinas M, et al. (2008)Cell Death Differ 15, 1510-21

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-981

List Size:
0.1 mg

List Price:

$355.00

Out of stock

Datasheet
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