IKK beta (Ab 199) Antibody

CATALOG NUMBER: 79-613

Clonality:
Polyclonal
Tested Applications:
IF, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
IKK-beta (Ab-199) antibody was raised against a peptide sequence around aa.197~201 (Q-K-Y-T-V) derived from Human IKK-β.
Conjugate:
Unconjugated
Tested Applications:
IF, WB
Application Note:
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Specificity:
This antibody detects endogenous level of total IKK-βprotein.
Predicted Molecular Weight:
87 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
IKBKB
Additional Names:
IKK2, IKKB, IMD15, NFKBIKB, IKK-beta, I-kappa-B kinase 2, I-kappa-B-kinase beta, IKK2, IkBKB
Protein Accession Number:
NP_001547.1
Protein Gi Number:
41352712
Ncbi Gene Id Number:
3551
Background:
Acts as part of the IKK complex in the conventional pathway of NF-κ-B activation and phosphorylates inhibitors of NF-κ-B thus leading to the dissociation of the inhibitor/NF-κ-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.
Background Reference 1:
Chen RA, et al. PLoS Pathog. 2008 Feb 8;4 (2): e22Yen CJ, et al. Cancer Res. 2008 Apr 15;68 (8): 2632-40

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-613

List Size:
0.1 mg

List Price:

$370.00

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