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Western blot analysis of extracts from 293 cells treated with TNF-a using Phospho-IKK- gamma (Ser31) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from 293 cells treated with TNF-a using Phospho-IKK- gamma (Ser31) Antibody. The lane on the right is treated with the antigen-specific peptide.

IKK- gamma (phospho Ser31) Antibody

CATALOG NUMBER: 80-016

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
IKK- gamma (phospho Ser31) antibody was raised against a peptide sequence around phosphorylation site of serine 31 (E-E-S (p)-P-L) derived from Human IKK-gamma.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous level of IKK- gamma only when phosphorylated at serine 31.
Predicted Molecular Weight:
48 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
IKBKG
Additional Names:
FIP-3, FIP3, I-kappa-B kinase gamma, IKBKG, IKKAP1
Protein Accession Number:
NP_001093326.2
Protein Gi Number:
3641279
Ncbi Gene Id Number:
8517
Background:
Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly.
Background Reference 1:
Carter RS, Pennington KN, Ungurait BJ, Ballard DW (2003)J Biol Chem 278, 19642-8.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

80-016

List Size:
0.1 mg

List Price:

$355.00

Out of stock

Datasheet
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