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IKK-γ (phospho Ser376) Antibody

CATALOG NUMBER: 79-846

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
IKK-γ (phospho Ser376) antibody was raised against a peptide sequence around phosphorylation site of Serine 376 (Y-L-S (p)-S-P) derived from Human IKK-γ.
Conjugate:
Unconjugated
Tested Applications:
IHC
Specificity:
The antibody detects endogenous levels of IKK-γ only when phosphorylated at serine 376.
Predicted Molecular Weight:
48 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
IKBKG
Additional Names:
FIP3, IKBKG, IKKAP1, IKKG, NF-kappaB
Protein Accession Number:
NP_001093327.1
Protein Gi Number:
3641279
Ncbi Gene Id Number:
8517
Background:
Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males. In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation.
Background Reference 1:
Li Y., Proc. Natl. Acad. Sci. U.S.A. 96:1042-1047(1999).
Background Reference 2:
Jin D.-Y., J. Biomed. Sci. 6:115-120(1999).
Background Reference 3:
Rothwarf D.M., Nature 395:297-300(1998).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-846

List Size:
0.1 mg

List Price:

$376.00

Datasheet
Shipping Info

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