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IL-1 beta Recombinant Protein

CATALOG NUMBER: 40-110

Specifications
source-species:
E. coli
Species:
Murine
source-species:
E. coli
Recombinant Protein Sequence:
MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS
Biological Activity:
The ED50 was determined by the dose - dependent stimulation of murine D10S cells is < 0.002 ng/mL, corresponding to a specific activity of > 5 x 108 units/mg.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized IL-1 beta recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-1 beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IL-1 beta recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
Il1b
Additional Names:
Il-1b, IL-1beta, Interleukin-1 beta, IL-1 beta
Protein Accession Number:
NP_032387.1
Protein Gi Number:
6680415
Ncbi Gene Id Number:
16176
Background:
IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant murine IL-1β is a 17.5 kDa protein containing 153 amino acid residues.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-110

List Size:
0.002 mg, 0.01 mg

List Price:

Price range: $215.00 through $323.00

Datasheet
Shipping Info

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