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IL-10 Recombinant Protein

CATALOG NUMBER: 90-555

Specifications
Source Species:
E. coli
Species:
Human
Source Species:
E. coli
Recombinant Protein Sequence:
Human IL-10 (aa 19-178) with a N-terminal Met.
Application Note:
This recombinant proteins is for research use only.
Predicted Molecular Weight:
~18kDa (SDS-PAGE)
Biological Activity:
Immobilized human IL-10 at 10ug/ml (100ul/well) can bind Cynomolgus IL-10RA-Fc. The EC50 of Cynomolgus IL-10RA-Fc is 0.24-0.56ug/ml.
Purity:
≥95% (SDS-PAGE).

Endotoxin level is less than <0.01EU/μg protein (LAL test; Lonza).
Physical State:
Lyophilized
Buffer:
Lyophilized from 0.2μm-filtered solution in 20mM Tris, 20mM NaCl, pH8.7.
Concentration:
0.1mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -80°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Ncbi Official Symbol:
IL10
Additional Names:
Interleukin-10; Cytokine Synthesis Inhibitory Factor; CSIF
Protein Accession Number:
NP_000563.1
Ncbi Gene Id Number:
3586
Background:
Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-555

List Size:
10 ug

List Price:

$350.00

Out of stock

Datasheet
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