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Human IL-17 RE (155-454), Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IL-17C, His Tag at 2 ug/mL (100 uL/well) can bind Human IL-17 RE (155-454), Fc Tag with a linear range of 1-10 ng/mL (QC tested).
Human IL-17 RE (155-454), Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

IL-17 RE (155-454) Recombinant Protein

CATALOG NUMBER: 11-285

Tested Applications:
ELISA, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Thr 155 - His 454
Fusion Tag:
Fc Tag
Tested Applications:
ELISA, WB
Application Note:
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.5 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Predicted Molecular Weight:
60.5 kDa
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
IL17RE
Additional Names:
IL-17 RE,IL17RE,IL-17RE,IL-17 receptor E
Protein Accession Number:
NP_705613.1
Ncbi Gene Id Number:
132014
Background:
Interleukin-17 receptor E (IL-17 RE) is an orphan receptor of the IL-17 receptor family, also known as UNQ3056, PRO9877, IL-17 Receptor E. IL-17RE is known to be expressed in the pancreas, brain, and prostate. IL-17RE is a receptor specific to IL-17C and has an essential role in host mucosal defense against infection. IL-17C functioned in a unique autocrine manner, binding to a receptor complex consisting of the receptors IL-17RA and IL-17RE, which was preferentially expressed on tissue epithelial cells. Some data identify IL-17RE as a receptor of IL-17C that regulates early innate immunity to intestinal pathogens.
Background Reference 1:
Song X. Nat Immunol. 2011. 12(12):1151-8.
Background Reference 2:
Ramirez-Carrozzi V. Nat Immunol. 2011. 12(12):1159-66.
Background Reference 3:
Pfeifer P. Am J Respir Cell Mol Biol. 2013. 48(4):415-21.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

11-285

List Size:
0.1 mg

List Price:

$577.00

Datasheet
Shipping Info

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