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Western blot analysis of IL-17RE in human ovary tissue lysate with IL-17RE antibody at 1 μg/mL.
Western blot analysis of IL-17RE in human ovary tissue lysate with IL-17RE antibody at 1 μg/mL.
Trial Size

IL-17RE Antibody

CATALOG NUMBER: 7181

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Rabbit polyclonal IL-17RE antibody was raised against a 16 amino acid peptide near the center of human IL-17RE.
The immunogen is located within amino acids 230 - 280 of IL-17RE.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
IL-17RE antibody can be used for detection of IL-17RE by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1316 - Human Ovary Tissue Lysate
Predicted Molecular Weight:
Predicted: 78 kDa
Purification:
IL-17RE Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
IL-17RE Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
IL-17RE antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Ncbi Official Symbol:
IL17RE
Additional Names:
IL-17RE Antibody: Interleukin-17 receptor E, IL-17 receptor E
Protein Accession Number:
NP_705616
Protein Gi Number:
301129232
Ncbi Gene Id Number:
132014
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
IL-17RE Antibody: The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
Background Reference 1:
Li TS, Li XN, Chang CJ, et al. Identification and functional characterization of a novel interleukin 17 receptor: a possible mitogenic activation through ras/mitogen-activated protein kinase signaling pathway. Cell Signal. 2006; 18:1287-98.
Background Reference 2:
Moseley TA, Haudenschild DR, Rose L, et al. Interleukin-17 family and IL-17 receptors. Cytokine Growth Factor Rev. 2003; 14:155-74.
Background Reference 3:
Song Z, Zhu S, Shi P, et al. IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens. Nat. Immunol. 2011; 12:1151-8.
Background Reference 4:
Ramirez-Carrozzi V, Sambandam A, Luis E, et al. IL-17C regulates the innate immune function of epithelial cells in an autocrine manner. Nat. Immunol. 2011; 12:1159-66

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

7181

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
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