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IL-18 Antibody [SB116c]

CATALOG NUMBER: 99-801

Clonality:
Monoclonal
Tested Applications:
E, EM, ICC, IHC-Fr, IHC-P, WB
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Immunogen:
E. coli-expressed human IL-18
Conjugate:
Unconjugated
Tested Applications:
E, EM, ICC, IHC-Fr, IHC-P, WB
Application Note:
IL-18 Antibody [SB116c] for use in ELISA assays.
Specificity:
IL-18
Clonality:
Monoclonal
Isotype:
IgG3
Physical State:
Liquid
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Storage Conditions:
Store vial at 2-8˚C
Ncbi Official Symbol:
IL18
Additional Names:
Interleukin-18, IFN-gamma-inducing factor, IL-1 gamma
Protein Accession Number:
Q14116
Ncbi Gene Id Number:
3606
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Interleukin-18 (IL-18), also known as IFN-gamma-inducing factor, is an 18 kDa protein and a member of the IL-1 family. This pro-inflammatory cytokine is primarily produced by antigen-presenting cells including monocytes/macrophages, as well as in keratinocytes and mucosal cell populations. Upon binding to target cells, IL-18 can induce natural killer (NK) cell activity, proliferation of activated T lymphocytes, and release of numerous pro-inflammatory cytokines. Moreover, this cytokine can promote Fas ligand expression in NK cells and enhance Fas ligand-mediated cytotoxicity of Th1 cells. Upregulation of IL-18 has been linked to several chronic inflammatory conditions including rheumatoid arthritis, heart disease and, atherosclerosis.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

99-801

List Size:
0.5 mg

List Price:

$365.00

Out of stock

Datasheet
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