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IL-2 Recombinant Protein

CATALOG NUMBER: 90-470

Specifications
source-species:
E. coli
Species:
Rat
source-species:
E. coli
Recombinant Protein Sequence:
Rat IL-2 (aa 21-155) is fused at the C-terminus to a His-tag.
Fusion Tag:
His Tag
Application Note:
This recombinant proteins is for research use only.
Purity:
>95% (SDS-PAGE).

Endotoxin level is less than 1EU/ μg protein (LAL test; Lonza).
physical-state:
Lyophilized
Buffer:
Lyophilized from 0.2um-filtered solution in PBS (pH 7.4). Reconstituted in sterile H2O not less than 100 μg/ml, which can then be further diluted in other aqueous solutions.
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Ncbi Official Symbol:
Il2
Additional Names:
Interleukin-2, Aldesleukin
Protein Accession Number:
NP_446288
Protein Gi Number:
16758692
Ncbi Gene Id Number:
116562
Background:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-470

List Size:
10 ug

List Price:

$328.00

Datasheet
Shipping Info

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