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IL-3 Recombinant Protein

CATALOG NUMBER: 40-618

Specifications
source-species:
E. coli
Species:
Murine
source-species:
E. coli
Recombinant Protein Sequence:
MDTHRLTRTL NCSSIVKEII GKLPEPELKT DDEGPSLRNK SFRRVNLSKF VESQGEVDPE DRYVIKSNLQ KLNCCLPTSA NDSALPGVFI RDLDDFRKKL RFYMVHLNDL ETVLTSRPPQ PASGSVSPNR GTVEC
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of the proliferation of mouse M-NFS-60 cells is =0.05 ng/mL, corresponding to a specific activity of = 2 x 107 units/mg.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
physical-state:
Lyophilized
Storage Conditions:
The lyophilized IL-3 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IL-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
Il3
Additional Names:
BPA, PSF, HCGF, Il-3, MCGF, Csfmu, Interleukin-3, Hematopoietic growth factor, IL-3
Protein Accession Number:
NP_034686.2
Protein Gi Number:
31982791
Ncbi Gene Id Number:
16187
Background:
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-618

List Size:
0.01 mg

List Price:

$370.00

Datasheet
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