IL-5 Recombinant Protein

CATALOG NUMBER: 40-434

Specifications
source-species:
E. coli
Species:
Murine
source-species:
E. coli
Recombinant Protein Sequence:
MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG
Biological Activity:
The ED50 was determined by the dose - dependent stimulation of the proliferation of human TF - 1 cells is < 2.0 ng/mL, corresponding to a specific activity of > 5 x 105 units/mg.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized IL-5 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-5 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IL-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
IL5
Additional Names:
EDF, TRF, IL-5, Interleukin-5, B-cell differentiation factor I
Protein Accession Number:
NP_000870.1
Protein Gi Number:
4504671
Ncbi Gene Id Number:
3567
Background:
IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-434

List Size:
0.005 mg, 0.025 mg

List Price:

Price range: $215.00 through $323.00

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