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Antibody used in WB on Human Jurkat 5.0 ug/ml.
Antibody used in WB on Human Jurkat 5.0 ug/ml.

IL10RA Antibody

CATALOG NUMBER: 30-047

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IL10RA.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
IL10RA antibody can be used for detection of IL10RA by ELISA at 1:312500. IL10RA antibody can be used for detection of IL10RA by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
61 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store IL10RA antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
IL10RA
Additional Names:
IL10RA, CDW210A, HIL-10R, IL-10R1, IL10R, CD210, CD210a
Protein Accession Number:
NP_001549
Protein Gi Number:
222136575
Ncbi Gene Id Number:
3587
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
Background Reference 1:
Gasche, C., (2003) J. Immunol. 170 (11), 5578-5582.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

30-047

List Size:
100 ul

List Price:

$473.00

Datasheet
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