IL17A Antibody

CATALOG NUMBER: XW-7289

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
37-193
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
IL17 antibody can be used for the detection of IL-17 by ELISA, Western blot, may also work for IHC and ICC.
Predicted Molecular Weight:
17.5 kDa (calculated)
Purification:
Antigen affinity-purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
IL17A antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
IL18
Additional Names:
IGIF, IL1F4, Interleukin-18, Iboctadekin, IL-18, IGIF, IL-1g,
Protein Accession Number:
NP_001553.1
Protein Gi Number:
4504653
Ncbi Gene Id Number:
3606
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Interleukin 17; cytotoxic T-lymphocyte-associated serine esterase 8. This protein is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-κB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis
Background Reference 1:
Nakae, S., Saijo, S., Horai, R., Sudo, K., Mori, S., Iwakura, Y. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc. Nat. Acad. Sci. 100: 5986-5990, 2003.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7289

List Size:
0.05 mg

List Price:

$615.00

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