IL1R1 Antibody

CATALOG NUMBER: 57-404

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This IL1R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of human IL1R1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
65 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
IL1R1
Additional Names:
Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a, Interleukin-1 receptor type 1, membrane form, mIL-1R1, mIL-1RI, Interleukin-1 receptor type 1, soluble form, sIL-1R1, sIL-1RI, IL1R1, IL1R, IL1RA, IL1RT1
Protein Accession Number:
P14778
Protein Gi Number:
124308
Ncbi Gene Id Number:
3554
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a cytokine receptorthat belongs to the interleukin 1 receptor family. This protein isa receptor for interleukin alpha (IL1A), interleukin beta (IL1B),and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an importantmediator involved in many cytokine induced immune and inflammatoryresponses. This gene along with interleukin 1 receptor, type II(IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in aregion mapped to chromosome 2q12.
Background Reference 1:
Fragoso, J.M., et al. Immunol. Lett. 133(2):106-111(2010)
Background Reference 2:
Franchim, C.S., et al. Hypertens Pregnancy (2010) In press :
Background Reference 3:
Melen, E., et al. J. Allergy Clin. Immunol. 126(3):631-637(2010)
Background Reference 4:
de Wit, E., et al. Mamm. Genome (2010) In press :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-404

List Size:
400 ul

List Price:

$495.00

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