IL1R2 Antibody

CATALOG NUMBER: 55-587

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This IL1R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 amino acids from the Central region of human IL1R2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
45 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
IL1R2
Additional Names:
Interleukin-1 receptor type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 antigen-like family member B, CDw121b, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II, CD121b, Interleukin-1 receptor type 2, membrane form, mIL-1R2, mIL-1RII, Interleukin-1 receptor type 2, soluble form, sIL-1R2, sIL-1RII, IL1R2, IL1RB
Protein Accession Number:
P27930
Protein Gi Number:
124310
Ncbi Gene Id Number:
7850
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a cytokine receptorthat belongs to the interleukin 1 receptor family. This proteinbinds interleukin alpha (IL1A), interleukin beta (IL1B), andinterleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoyreceptor that inhibits the activity of its ligands. Interleukin 4(IL4) is reported to antagonize the activity of interleukin 1 byinducing the expression and release of this cytokine. This gene andthree other genes form a cytokine receptor gene cluster onchromosome 2q12. Two alternatively spliced transcript variantsencoding the same protein have been reported.
Background Reference 1:
Giroux, S., et al. Bone 47(5):975-981(2010)
Background Reference 2:
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Background Reference 3:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 4:
Chen, C., et al. Rheumatol. Int. (2010) In press :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-587

List Size:
400 ul

List Price:

$495.00

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