IL22RA2 Antibody

CATALOG NUMBER: 59-974

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This IL22RA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-42 amino acids from the N-terminal region of human IL22RA2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
31 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
IL22RA2
Additional Names:
Interleukin-22 receptor subunit alpha-2, IL-22 receptor subunit alpha-2, IL-22R-alpha-2, IL-22RA2, Cytokine receptor class-II member 10, Cytokine receptor family 2 member 10, CRF2-10, Cytokine receptor family type 2, soluble 1, CRF2-S1, Interleukin-22-binding protein, IL-22BP, IL22BP, ZcytoR16, IL22RA2
Protein Accession Number:
Q969J5
Protein Gi Number:
61213728
Ncbi Gene Id Number:
116379
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a soluble class IIcytokine receptor. This protein has been shown to specifically bindto interleukin 22 (IL22), block the interaction of IL22 with itscell surface receptor, and thus inhibit IL22 activity. This proteinfunctions as an IL22 antagonist, and may be important in theregulation of inflammatory response. Three alternatively splicedtranscript variants encoding distinct isoforms have been described.
Background Reference 1:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 2:
Kingo, K., et al. J. Dermatol. Sci. 57(1):71-73(2010)
Background Reference 3:
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Background Reference 4:
Endam, L.M., et al. Otolaryngol Head Neck Surg 140(5):741-747(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-974

List Size:
400 ul

List Price:

$495.00

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