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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

IL5RA Antibody

CATALOG NUMBER: 60-404

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This IL5RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-420 amino acids from the C-terminal region of human IL5RA.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
48 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
IL5RA
Additional Names:
Interleukin-5 receptor subunit alpha, IL-5 receptor subunit alpha, IL-5R subunit alpha, IL-5R-alpha, IL-5RA, CDw125, CD125, IL5RA, IL5R
Protein Accession Number:
Q01344
Protein Gi Number:
116242525
Ncbi Gene Id Number:
3568
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is an interleukin 5specific subunit of a heterodimeric cytokine receptor. The receptoris comprised of a ligand specific alpha subunit and a signaltransducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The binding of this protein to IL5 depends on the betasubunit. The beta subunit is activated by the ligand binding, andis required for the biological activities of IL5. This protein hasbeen found to interact with syndecan binding protein (syntenin),which is required for IL5 mediated activation of the transcriptionfactor SOX4. Six alternatively spliced transcript variants encodingthree distinct isoforms have been reported.
Background Reference 1:
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Background Reference 2:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 3:
Beckers, M.M., et al. Eur. J. Intern. Med. 21(4):289-292(2010)
Background Reference 4:
Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-404

List Size:
400 ul

List Price:

$495.00

Datasheet
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