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Western blot analysis in 293 cell line lysates (35ug/lane).
Confocal immunofluorescent analysis of IMPDH1 Antibody with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
IMPDH1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in 293 cell line lysates (35ug/lane).

IMPDH1 Antibody

CATALOG NUMBER: 57-112

Clonality:
Polyclonal
Tested Applications:
IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This IMPDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-514 amino acids from the C-terminal region of human IMPDH1.
Conjugate:
Unconjugated
Tested Applications:
IF, IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
55 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
IMPDH1
Additional Names:
Inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255, HAMAP-Rule:MF_03156}, IMP dehydrogenase 1 {ECO:0000255, HAMAP-Rule:MF_03156}, IMPD 1 {ECO:0000255, HAMAP-Rule:MF_03156}, IMPDH 1 {ECO:0000255, HAMAP-Rule:MF_03156}, 111205 {ECO:0000255, HAMAP-Rule:MF_03156}, IMPDH-I, IMPDH1 {ECO:0000255, HAMAP-Rule:MF_03156}, IMPD1
Protein Accession Number:
P20839
Protein Gi Number:
25014074
Ncbi Gene Id Number:
3614
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
Background Reference 1:
Ohmann, E.L., et al. Pediatr Transplant 14(7):891-895(2010) Gensburger, O., et al. Pharmacogenet. Genomics 20(9):537-543(2010) Kagaya, H., et al. Basic Clin. Pharmacol. Toxicol. 107(2):631-636(2010) Ohmann, E.L., et al. J. Heart Lung Transplant. 29(5):509-516(2010) Shumei, L., et al. Adv. Exp. Med. Biol. 664, 293-297 (2010) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-112

List Size:
400 ul

List Price:

$495.00

Datasheet
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