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Western blot analysis in Ramos cell line lysates (35ug/lane).
Western blot analysis in Ramos cell line lysates (35ug/lane).

IQCB1 Antibody

CATALOG NUMBER: 58-917

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This IQCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-411 amino acids from the Central region of human IQCB1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
69 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
IQCB1
Additional Names:
IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ, IQCB1, KIAA0036, NPHP5
Protein Accession Number:
Q15051
Protein Gi Number:
3123054
Ncbi Gene Id Number:
9657
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a nephrocystin protein that interactswith calmodulin and the retinitis pigmentosa GTPase regulatorprotein. The encoded protein has a central coiled-coil region andtwo calmodulin-binding IQ domains. It is localized to the primarycilia of renal epithelial cells and connecting cilia ofphotoreceptor cells. The protein is thought to play a role inciliary function. Defects in this gene result in Senior-Lokensyndrome type 5. Alternative splicing results in multipletranscript variants.
Background Reference 1:
Hildebrandt, F., et al. J. Am. Soc. Nephrol. 20(1):23-35(2009)
Background Reference 2:
Schafer, T., et al. Hum. Mol. Genet. 17(23):3655-3662(2008)
Background Reference 3:
Luo, X., et al. Cancer Res. 65(23):10725-10733(2005)
Background Reference 4:
le Maire, A., et al. Proteins 59(2):347-355(2005)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-917

List Size:
400 ul

List Price:

$495.00

Datasheet
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