IRAK1 (phospho Ser376) Antibody

CATALOG NUMBER: 79-849

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
IRAK1 (phospho Ser376) antibody was raised against a peptide sequence around phosphorylation site of Serine 376 (Q-S-S (p)-M-V) derived from Human IRAK1.
Conjugate:
Unconjugated
Tested Applications:
IHC
Specificity:
The antibody detects endogenous levels of IRAK1 only when phosphorylated at serine 376.
Predicted Molecular Weight:
76 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
IRAK1
Additional Names:
IL1RAK, IRAK, mPLK
Protein Accession Number:
NP_001560.2
Protein Gi Number:
8928535
Ncbi Gene Id Number:
3654
Background:
IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.
Background Reference 1:
Cao Z., Science 271:1128-1131(1996).
Background Reference 2:
Reichwald K., Mamm. Genome 11:182-190(2000).
Background Reference 3:
Jensen L.E., J. Biol. Chem. 276:29037-29044(2001).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-849

List Size:
0.1 mg

List Price:

$376.00

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