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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

IRF1 Antibody

CATALOG NUMBER: 56-084

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Immunogen:
This IRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the Central region of human IRF1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
37 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
IRF1
Additional Names:
Interferon regulatory factor 1, IRF-1, IRF1
Protein Accession Number:
P10914
Protein Gi Number:
20178295
Ncbi Gene Id Number:
3659
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
IRF1 encodes interferon regulatory factor 1, a member ofthe interferon regulatory transcription factor (IRF) family. IRF1serves as an activator of interferons alpha and beta transcription,and in mouse it has been shown to be required for double-strandedRNA induction of these genes. IRF1 also functions as atranscription activator of genes induced by interferons alpha,beta, and gamma. Further, IRF1 has been shown to play roles inregulating apoptosis and tumor-suppressoion.
Background Reference 1:
Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
Background Reference 2:
Matsuzaki, S., et al. J. Immunol. 185(8):4863-4872(2010)
Background Reference 3:
Antonios, D., et al. J. Immunol. 185(1):89-98(2010)
Background Reference 4:
Lou, Y.J., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27(3):255-258(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-084

List Size:
400 ul

List Price:

$495.00

Datasheet
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