IRF5 Antibody

CATALOG NUMBER: 28-629

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse IRF5.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
IRF5 antibody can be used for detection of IRF5 by ELISA at 1:62500. IRF5 antibody can be used for detection of IRF5 by western blot at 0.15 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1369 - Human Lymph node Tissue Lysate
Predicted Molecular Weight:
55 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store IRF5 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
IRF5
Additional Names:
IRF5, mirf5, AW491843
Protein Accession Number:
NP_036187
Protein Gi Number:
6754368
Ncbi Gene Id Number:
27056
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha.
Background Reference 1:
Takaoka, A., et al., (2005) Nature 434 (7030), 243-249.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-629

List Size:
100 ul

List Price:

$519.00

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