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Antibody used in IHC on Human kidney.
Antibody used in WB on Human Jurkat 1.25 ug/ml.
Antibody used in IHC on Human kidney.

IRF8 Antibody

CATALOG NUMBER: 31-203

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat, Zebrafish
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat, Zebrafish
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRF8.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
IRF8 antibody can be used for detection of IRF8 by ELISA at 1:62500. IRF8 antibody can be used for detection of IRF8 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
48 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store IRF8 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
IRF8
Additional Names:
IRF8, ICSBP, IRF-8, ICSBP1, H-ICSBP
Protein Accession Number:
NP_002154
Protein Gi Number:
4504567
Ncbi Gene Id Number:
3394
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Interferon consensus sequence-binding protein (Ion ChannelSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Background Reference 1:
Kebin Liu, et al., (2007) Cancer Res 67:3301.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

31-203

List Size:
100 ul

List Price:

$473.00

Datasheet
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