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IRGB10 (NT) Peptide

CATALOG NUMBER: 9513P

Tested Applications:
Blocking
Specifications
Peptide Aa Location:
13 amino acids near the amino terminus of IRGB10 (NT).
Species:
Mouse
Tested Applications:
Blocking
Application Note:
IRGB10 (NT) Peptideis used for blocking the activity of theIRGB10 (NT) Antibody
Physical State:
Liquid
Buffer:
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and ≤0.09% sodium azide
Concentration:
200 ug/mL
Storage Conditions:
Store IRGB10 (NT) Peptide at -20°C, stable for one year.
Ncbi Official Symbol:
IRGB10
Additional Names:
IRGB10 Antibody: Immunity-related GTPase family member b10, Interferon-gamma-inducible p47 GTPase, Gm12250, OTTMUSG00000005723
Protein Accession Number:
AGY29631
Protein Gi Number:
551032829
Ncbi Gene Id Number:
631323
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
IRGB10 Antibody: IRGB10 is an inferno-inducible protein that is essential for the activation of DNA-sensing AIM2 inflammasome, and contributes to the activation of LPS-sensing caspase-11 and NLRP3 inflammasome. IRGB10 is part of a conserved signaling hub at the interface between cell-autonomous immunity and innate immune sensing pathways. IRGB10 targets cytoplasmic bacteria and compromises bacterial structural integrity. IRGB10 and LIGP2 act together to confer differential susceptibility against Chlamydia infection in mice.
Background Reference 1:
Man et al. Cell 2016; 167(2):382-396.e17
Background Reference 2:
Bernstein-Hanley I et al. Proc Natl Acad Sci USA. 2006;103(38):14092-14097
Background Reference 3:
Miyairi I et al. J Immunol 2007; 179(3):1814-1824
Background Reference 4:
Coers J et al. J Immunol 2008; 180(9):6237-6245

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

9513P

List Size:
0.05 mg

List Price:

$119.00

Datasheet
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