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Western blot analysis in WiDr cell line lysates (35ug/lane).
Western blot analysis in mouse lung tissue lysates (35ug/lane).
Western blot analysis in WiDr cell line lysates (35ug/lane).

ISCU Antibody

CATALOG NUMBER: 60-893

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This ISCU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the C-terminal region of human ISCU.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
18 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ISCU
Additional Names:
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial, NifU-like N-terminal domain-containing protein, NifU-like protein, ISCU, NIFUN
Protein Accession Number:
Q9H1K1
Protein Gi Number:
313104118
Ncbi Gene Id Number:
23479
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Iron-sulfur (Fe-S) clusters are necessary for severalmitochondrial enzymes and other subcellular compartment proteins.They contain sulfur and iron, and are created via several stepsthat include cysteine desulfurases, iron donors, chaperones, andscaffold proteins. This gene encodes the two isomeric forms, ISCU1and ISCU2, of the Fe-S cluster scaffold protein. Mutations in thisgene have been found in patients with myopathy with severe exerciseintolerance and myoglobinuria.
Background Reference 1:
Chen, Z., et al. Oncogene 29(30):4362-4368(2010)
Background Reference 2:
Chan, S.Y., et al. Cell Metab. 10(4):273-284(2009)
Background Reference 3:
Kollberg, G., et al. Brain 132 (PT 8), 2170-2179 (2009) :
Background Reference 4:
Huang, J., et al. J. Biol. Inorg. Chem. 13(5):825-836(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-893

List Size:
400 ul

List Price:

$495.00

Datasheet
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