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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Western blot analysis in mouse bladder tissue lysates (35ug/lane).
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

ISL1 Antibody

CATALOG NUMBER: 58-426

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Zebrafish, Rat
Immunogen:
This ISL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ISL1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
39 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ISL1
Additional Names:
Insulin gene enhancer protein ISL-1, Islet-1, ISL1
Protein Accession Number:
P61371
Protein Gi Number:
47606423
Ncbi Gene Id Number:
3670
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ISL1 is a member of the LIM/homeodomain familyof transcription factors. The encoded protein binds to the enhancerregion of the insulin gene, among others, and may play an importantrole in regulating insulin gene expression. The encoded protein iscentral to the development of pancreatic cell lineages and may alsobe required for motor neuron generation. Mutations in this genehave been associated with maturity-onset diabetes of the young.
Background Reference 1:
De Luca, A., et al. Clin. Genet. (2010) In press :
Background Reference 2:
Davis, O.S., et al. Behav. Genet. (2010) In press :
Background Reference 3:
Genead, R., et al. Stem Cell Res 4(1):69-76(2010)
Background Reference 4:
Stevens, K.N., et al. PLoS ONE(5), E10855 (2010) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-426

List Size:
400 ul

List Price:

$495.00

Datasheet
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