ITGA5 Antibody

CATALOG NUMBER: 56-279

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ITGA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-602 amino acids from the Central region of human ITGA5.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
115 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ITGA5
Additional Names:
Integrin alpha-5, CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD49e, Integrin alpha-5 heavy chain, Integrin alpha-5 light chain, ITGA5, FNRA
Protein Accession Number:
P08648
Protein Gi Number:
23831237
Ncbi Gene Id Number:
3678
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The product of this gene belongs to the integrin alphachain family. Integrins are heterodimeric integral membraneproteins composed of an alpha chain and a beta chain. This geneencodes the integrin alpha 5 chain. Alpha chain 5 undergoespost-translational cleavage in the extracellular domain to yielddisulfide-linked light and heavy chains that join with beta 1 toform a fibronectin receptor. In addition to adhesion, integrins areknown to participate in cell-surface mediated signalling. [providedby RefSeq].
Background Reference 1:
Hutton, M.L., et al. Infect. Immun. 78(11):4523-4531(2010)
Background Reference 2:
Fang, Z., et al. J. Cell. Biochem. 110(5):1130-1141(2010)
Background Reference 3:
Lobert, V.H., et al. Dev. Cell 19(1):148-159(2010)
Background Reference 4:
Caicedo-Carvajal, C.E., et al. PLoS ONE(7), E11830 (2010) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-279

List Size:
400 ul

List Price:

$495.00

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