ITGA7 Antibody

CATALOG NUMBER: 60-160

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ITGA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-257 amino acids from the N-terminal region of human ITGA7.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
129 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ITGA7
Additional Names:
Integrin alpha-7, Integrin alpha-7 heavy chain, Integrin alpha-7 light chain, Integrin alpha-7 70 kDa form, ITGA7
Protein Accession Number:
Q13683
Protein Gi Number:
308153592
Ncbi Gene Id Number:
3679
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene belongs to the integrinalpha chain family. Integrins are heterodimeric integral membraneproteins composed of an alpha chain and a beta chain. They mediatea wide spectrum of cell-cell and cell-matrix interactions, and thusplay a role in cell migration, morphologic development,differentiation, and metastasis. This protein functions as areceptor for the basement membrane protein laminin-1. It is mainlyexpressed in skeletal and cardiac muscles and may be involved indifferentiation and migration processes during myogenesis. Defectsin this gene are associated with congenital myopathy. Alternativelyspliced transcript variants encoding different isoforms have beennoted for this gene.
Background Reference 1:
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Background Reference 2:
Han, Y.C., et al. Cancer Res. 70(11):4375-4384(2010)
Background Reference 3:
Rooney, J.E., et al. Proc. Natl. Acad. Sci. U.S.A. 106(19):7991-7996(2009)
Background Reference 4:
Liu, J., et al. J. Biol. Chem. 283(51):35668-35678(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-160

List Size:
400 ul

List Price:

$495.00

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