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Western blot analysis in K562 cell line lysates (35ug/lane).
ITGA8 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in K562 cell line lysates (35ug/lane).

ITGA8 Antibody

CATALOG NUMBER: 55-928

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ITGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1053 amino acids from the C-terminal region of human ITGA8.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
117 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ITGA8
Additional Names:
Integrin alpha-8, Integrin alpha-8 heavy chain, Integrin alpha-8 light chain, ITGA8
Protein Accession Number:
P53708
Protein Gi Number:
311033437
Ncbi Gene Id Number:
8516
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.
Background Reference 1:
Benoit, Y.D., et al. Biochem. Biophys. Res. Commun. 399(3):434-439(2010)
Background Reference 2:
Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009)
Background Reference 3:
Benoit, Y.D., et al. Biol. Cell 101(12):695-708(2009)
Background Reference 4:
Sato, Y., et al. J. Biol. Chem. 284(21):14524-14536(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-928

List Size:
400 ul

List Price:

$495.00

Datasheet
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