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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

ITGAE Antibody

CATALOG NUMBER: 55-218

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ITGAE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1146-1173 amino acids from the C-terminal region of human ITGAE.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
130 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ITGAE
Additional Names:
Integrin alpha-E, HML-1 antigen, Integrin alpha-IEL, Mucosal lymphocyte 1 antigen, CD103, Integrin alpha-E light chain, Integrin alpha-E heavy chain, ITGAE
Protein Accession Number:
P38570
Protein Gi Number:
226694184
Ncbi Gene Id Number:
3682
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Integrins are heterodimeric integral membrane proteinscomposed of an alpha chain and a beta chain. ITGAE encodes anI-domain-containing alpha integrin that undergoespost-translational cleavage in the extracellular domain, yieldingdisulfide-linked heavy and light chains. In combination with thebeta 7 integrin, this protein forms the E-cadherin binding integrinknown as the human mucosal lymphocyte-1 antigen. This protein ispreferentially expressed in human intestinal intraepitheliallymphocytes (IEL), and in addition to a role in adhesion, it mayserve as an accessory molecule for IEL activation. [provided byRefSeq].
Background Reference 1:
Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
Background Reference 2:
Liu, Y.H., et al. Ophthalmology 117(8):1645-1651(2010)
Background Reference 3:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 4:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-218

List Size:
400 ul

List Price:

$495.00

Datasheet
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