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Western blot analysis in MCF-7 cell line lysates (35ug/lane).
Western blot analysis in MCF-7 cell line lysates (35ug/lane).

ITGB1BP1 Antibody

CATALOG NUMBER: 59-287

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This ITGB1BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-136 amino acids from the Central region of human ITGB1BP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
22 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ITGB1BP1
Additional Names:
Integrin beta-1-binding protein 1, Integrin cytoplasmic domain-associated protein 1, ICAP-1, ITGB1BP1, ICAP1
Protein Accession Number:
O14713
Ncbi Gene Id Number:
9270
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The cytoplasmic domains of integrins are essential forcell adhesion. The protein encoded by this gene binds to the beta1integrin cytoplasmic domain. The interaction between this proteinand beta1 integrin is highly specific. Two isoforms of this proteinare derived from alternatively spliced transcripts. The shorterform of this protein does not interact with the beta1 integrincytoplasmic domain. The longer form is a phosphoprotein and theextent of its phosphorylation is regulated by the cell-matrixinteraction, suggesting an important role of this protein duringintegrin-dependent cell adhesion.
Background Reference 1:
Brutsch, R., et al. Circ. Res. 107(5):592-601(2010)
Background Reference 2:
Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)
Background Reference 3:
Zhang, J., et al. Neurosurgery 63(3):571-578(2008)
Background Reference 4:
Furusu, A., et al. J. Cell. Physiol. 210(3):703-710(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-287

List Size:
400 ul

List Price:

$495.00

Datasheet
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