ITPA Antibody

CATALOG NUMBER: 60-226

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ITPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the C-terminal region of human ITPA.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
21 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ITPA
Additional Names:
Inosine triphosphate pyrophosphatase {ECO:0000255, HAMAP-Rule:MF_03148}, ITPase {ECO:0000255, HAMAP-Rule:MF_03148}, Inosine triphosphatase {ECO:0000255, HAMAP-Rule:MF_03148}, 36119 {ECO:0000255, HAMAP-Rule:MF_03148}, Non-canonical purine NTP pyrophosphatase {ECO:0000255, HAMAP-Rule:MF_03148}, Non-standard purine NTP pyrophosphatase {ECO:0000255, HAMAP-Rule:MF_03148}, Nucleoside-triphosphate diphosphatase {ECO:0000255, HAMAP-Rule:MF_03148}, Nucleoside-triphosphate pyrophosphatase {ECO:0000255, HAMAP-Rule:MF_03148}, NTPase {ECO:0000255, HAMAP-Rule:MF_03148}, Putative oncogene protein hlc14-06-p, ITPA {ECO:0000255, HAMAP-Rule:MF_03148}, C20orf37
Protein Accession Number:
Q9BY32
Protein Gi Number:
30173120
Ncbi Gene Id Number:
3704
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene hydrolyzes inosinetriphosphate and deoxyinosine triphosphate to the monophosphatenucleotide and diphosphate. The encoded protein, which is a memberof the HAM1 NTPase protein family, is found in the cytoplasm andacts as a homodimer. Defects in the encoded protein can result ininosine triphosphate pyrophosphorylase deficiency. Two transcriptvariants encoding two different isoforms have been found for thisgene. Also, at least two other transcript variants have beenidentified which are probably regulatory rather thanprotein-coding.
Background Reference 1:
Kim, J.H., et al. J. Clin. Gastroenterol. 44 (10), E242-E248 (2010) :
Background Reference 2:
Ochi, H., et al. Gastroenterology 139(4):1190-1197(2010)
Background Reference 3:
Thompson, A.J., et al. Gastroenterology 139(4):1181-1189(2010)
Background Reference 4:
Ban, H., et al. J. Gastroenterol. 45(10):1014-1021(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-226

List Size:
400 ul

List Price:

$495.00

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