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Jagged-1 Antibody [J1G53-3]

CATALOG NUMBER: 36-051

Clonality:
Monoclonal
Tested Applications:
ELISA, Flow, IHC, WB
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Immunogen:
Recombinant human Jagged-1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, Flow, IHC, WB
Application Note:
ELISA: (direct or indirect: 1:500-1:5,000). Flow Cytometry: (1:20-1:100). Immunohistochemistry: (paraffin sections). Western blot: (1:500-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). Optimal conditions should be determined individually for each application.
Specificity:
Recognizes human Jagged-1. Detects a band of ~180kDa by Western blot.
Clonality:
Monoclonal
Isotype:
IgG1, kappa
Physical State:
Liquid
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
JAG1
Additional Names:
Protein Jagged-1; CD339; JAG1
Protein Accession Number:
4557679
Protein Gi Number:
NP_000205
Ncbi Gene Id Number:
182
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-051

List Size:
100 ug

List Price:

$408.00

Datasheet
Shipping Info

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