Jagged-2 Recombinant Protein

CATALOG NUMBER: 90-167

Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.
Fusion Tag:
Fc Tag
Application Note:
This recombinant proteins is for research use only.
Purity:
>90% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
physical-state:
Lyophilized
Buffer:
Contains PBS + 0.02 % CHAPS. Reconstitute with 100 μl sterile water.
Concentration:
0.1mg/ml after reconstitution.
Storage Conditions:
Stable for at least 6 months after receipt when stored at -20°C.
Ncbi Official Symbol:
JAG2
Additional Names:
Protein Jagged-2, hJ2, JAG2
Protein Accession Number:
Q9Y219
Protein Gi Number:
21704277
Ncbi Gene Id Number:
3714
Background:
Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-167

List Size:
10 ug

List Price:

$391.00

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