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Janus kinase 2 (phospho Tyr372) Antibody

CATALOG NUMBER: 39-866

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to the pY372 region.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Purification:
Affinity Purified
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Concentration:
batch dependent
Ncbi Official Symbol:
JAK2
Additional Names:
Janus kinase 2-pY372-phospho specific, Janus kinase 2,
Protein Accession Number:
BAG63863
Protein Gi Number:
12643404
Ncbi Gene Id Number:
12643404
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Janus Kinase 2 (JAK2) is essential for signaling thorough a variety of cytokine receptors. Phosphorylation of JAK is essential for downstream signaling. JAK kinases are known to phosphorylate several substrate including members of the STAT family of proteins
Background Reference 1:
Issam McDoom, Xianyue Ma, Annet Kirabo, Kuang-Yung Lee, David A. Ostrov and Peter P. Sayeski., Identification of Tyrosine 972 as a Novel Site of Jak2 Tyrosine Kinase Phosphorylation and Its Role in Jak2 Activation., Biochemistry, 2008, 47 (32), pp 8326-8334
Background Reference 2:
Parganas E, Wang D, Stravopodis D, Topham DJ, Marine JC, Teglund S, Vanin EF, Bodner S, Colamonici OR, van Deursen JM, Grosveld G, Ihle JN., Jak2 is essential for signaling through a variety of cytokine receptors., Cell. 1998 May 1;93(3):385-95.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

39-866

List Size:
0.05 mg

List Price:

$626.00

Datasheet
Shipping Info

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