JIK Antibody

CATALOG NUMBER: 62-589

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat, Xenopus
Immunogen:
This JIK (TAOK3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-700 amino acids from the C-terminal region of human JIK (TAOK3).
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
105 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TAOK3
Additional Names:
Serine/threonine-protein kinase TAO3, Cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK/SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, hKFC-A, Thousand and one amino acid protein 3, TAOK3, DPK, JIK, KDS, MAP3K18
Protein Accession Number:
Q9H2K8
Protein Gi Number:
78099183
Ncbi Gene Id Number:
51347
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TAOK3 is negatively regulated by epidermal growth factor (EGF) and Inhibits the basal activity of Jun kinase. When TAOK3 is overexpressed, it may activate ERK1/ERK2 and JNK/SAPK.
Background Reference 1:
Hartmann,T.B.,Br. J. Dermatol. 150 (2), 252-258 (2004)
Background Reference 2:
Yustein,J.T.,Oncogene 22 (40), 6129-6141 (2003)
Background Reference 3:
Yoneda,T.,J. Biol. Chem. 276 (17), 13935-13940 (2001)
Background Reference 4:
Zhang,W.,Biochem. Biophys. Res. Commun. 274 (3), 872-879 (2000)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-589

List Size:
400 ul

List Price:

$495.00

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