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Antibody used in WB on Human Jurkat 1 ug/ml.
Antibody used in WB on Human Jurkat 1 ug/ml.

JMJD2C Antibody

CATALOG NUMBER: 25-106

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human JMJD2C.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
JMJD2C antibody can be used for detection of JMJD2C by ELISA at 1:62500. JMJD2C antibody can be used for detection of JMJD2C by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
120 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store JMJD2C antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
KDM4C
Additional Names:
JMJD2C, FLJ25949, GASC1, JHDM3C, KDM4C, KIAA0780, bA146B14.1, JMJD2C, TDRD14C
Protein Accession Number:
NP_055876
Protein Gi Number:
109255247
Ncbi Gene Id Number:
23081
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.
Background Reference 1:
Katoh, Y. (2007) Int. J. Mol. Med. 20 (2), 269-273.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-106

List Size:
100 ul

List Price:

$519.00

Datasheet
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